Ernest Mario previously served as Chairman and Chief Executive Officer of ALZA Corporation from 1993 to 2001. Dr. Mario previously served on the boards of directors of GlaxoSmithKline plc, Cepheid Inc., Cor Therapeutics, Inc., Millennium Pharmaceuticals, Inc., Sonosite Inc., Catalytica Energy Systems, Inc., Orchid Cellmark, Inc., IntraBiotics Pharmaceuticals, Inc., Alexza Pharmaceuticals, Inc., Pharmaceutical Product Development Inc., Vivus, Inc. and Maxygen, Inc. He currently serves on the boards of directors of Boston Scientific Corporation, Celgene Corporation, XenoPort, Inc., Chimerix, Inc., Tonix Pharmaceuticals Holding Corp. and Kindred Biosciences, Inc.